If you’ve been prescribed Indocin, you’re probably wondering how it helps and what to watch out for. Indocin is the brand name for indomethacin, a powerful NSAID that reduces inflammation and eases pain. It’s often used for arthritis, gout attacks, and certain types of headaches. Below you’ll get straight‑forward advice on dosing, side effects, and safety, so you can feel confident about taking it.
Indocin blocks enzymes called COX‑1 and COX‑2, which produce prostaglandins – chemicals that cause swelling and pain. By cutting down prostaglandin production, the drug calms inflamed tissue and lowers fever. Doctors typically prescribe it for conditions that need quick, strong relief, such as acute gout flare‑ups, rheumatoid arthritis, ankylosing spondylitis, and bursitis. Because it’s more potent than over‑the‑counter NSAIDs, you’ll usually start it at a low dose and adjust as needed.
Adults often start with 25 mg two or three times a day. Some patients need 50 mg two times daily, but the maximum daily dose should not exceed 150 mg. Take the tablet with food or milk to lessen stomach upset – never take it on an empty stomach. If you miss a dose, take it as soon as you remember, unless it’s almost time for the next one; then skip the missed dose and stay on schedule. Don’t double up.
For kids, dosing is weight‑based and only used in special cases, so follow your pediatrician’s exact instructions. Swallow the tablet whole; crushing or chewing can irritate your mouth and stomach.
When you start Indocin, keep an eye on how you feel. Some people notice stomach discomfort, nausea, or a mild headache within the first few days. If those symptoms stay mild, food and a lower dose often help. But if you get severe stomach pain, black or bloody stools, or a sudden rash, call your doctor right away – those can be signs of serious side effects.
Most side effects are mild and go away on their own. Expect possible nausea, indigestion, or a light headache. Indocin can also raise your blood pressure, so check it regularly if you have hypertension. Less common but important issues include kidney trouble (especially if you’re dehydrated) and liver enzyme changes. Blood tests before starting treatment and after a few weeks help catch any problems early.
Watch out for signs of an ulcer: burning stomach pain that improves after eating, or vomiting blood. If you notice any of these, stop the medication and get medical help. Also, avoid alcohol while on Indocin because it can increase stomach irritation.
Indocin can interact with several medicines. Blood thinners like warfarin may become more potent, raising bleeding risk. If you’re on heart medicines such as ACE inhibitors, diuretics, or beta‑blockers, your kidneys might need closer monitoring. Combining Indocin with other NSAIDs (ibuprofen, naproxen) isn’t recommended – it just ups the chance of stomach bleeding.
Talk to your pharmacist before adding over‑the‑counter supplements. Some herbal products, especially ginkgo or high‑dose fish oil, can also affect bleeding risk.
Stay hydrated – drinking plenty of water protects your kidneys while you’re on an NSAID. Pair Indocin with a low‑acid diet (think oatmeal, bananas, yogurt) if you’re prone to heartburn. If you need long‑term pain control, discuss alternatives with your doctor; sometimes a COX‑2 selective NSAID or a different class of pain reliever works better with fewer side effects.
Never share your Indocin with anyone else, even if they have similar symptoms. The dosage and risk profile are specific to each person’s health picture.
Bottom line: Indocin is a strong tool for fast inflammation relief, but it demands respect. Follow your prescribed dose, eat it with food, watch for warning signs, and keep regular check‑ups. With those steps, you can manage pain effectively while staying safe.
Sep, 11 2025
A plain‑English guide to Indocin (indomethacin): what it treats, dosing, how to take it safely, side effects, interactions, warnings, and when to consider alternatives.